Plant Transcription Factor Database
Previous version: v3.0
Picea abies
WRKY Family
Species TF ID Description
MA_101135g0010WRKY family protein
MA_103616g0010WRKY family protein
MA_10425932g0020WRKY family protein
MA_10426648g0010WRKY family protein
MA_10426942g0010WRKY family protein
MA_10428170g0010WRKY family protein
MA_10432362g0010WRKY family protein
MA_10432914g0010WRKY family protein
MA_10434450g0010WRKY family protein
MA_10434651g0010WRKY family protein
MA_10434976g0010WRKY family protein
MA_10436051g0010WRKY family protein
MA_10436931g0040WRKY family protein
MA_107950g0010WRKY family protein
MA_109104g0010WRKY family protein
MA_11492g0010WRKY family protein
MA_120697g0010WRKY family protein
MA_120969g0010WRKY family protein
MA_124797g0010WRKY family protein
MA_126273g0010WRKY family protein
MA_134559g0010WRKY family protein
MA_136551g0010WRKY family protein
MA_138256g0010WRKY family protein
MA_14480g0020WRKY family protein
MA_16118g0010WRKY family protein
MA_161426g0010WRKY family protein
MA_164675g0010WRKY family protein
MA_175750g0010WRKY family protein
MA_179641g0010WRKY family protein
MA_20468g0010WRKY family protein
MA_212937g0010WRKY family protein
MA_2290g0010WRKY family protein
MA_23415g0010WRKY family protein
MA_381058g0010WRKY family protein
MA_426605g0010WRKY family protein
MA_46529g0010WRKY family protein
MA_47307g0010WRKY family protein
MA_496691g0010WRKY family protein
MA_52928g0010WRKY family protein
MA_53351g0010WRKY family protein
MA_54954g0010WRKY family protein
MA_6177g0010WRKY family protein
MA_65782g0010WRKY family protein
MA_6943842g0010WRKY family protein
MA_74833g0010WRKY family protein
MA_7513437g0010WRKY family protein
MA_88419g0010WRKY family protein
MA_91468g0010WRKY family protein
MA_934202g0010WRKY family protein
MA_93790g0010WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701